Prominent Neurologist and Pain Specialist relocates to Houston


A leading Pain Medicine physician and Neurologist who has spent several decades researching brain aging has joined the faculty of the University of Texas Medical Branch and established his private practice in Houston and Pasadena Texas as part of a National Institutes of Health program geared to boost the output of applied research.

Miguel A. Pappolla, M.D., Ph.D. a former S.C. Research Centers of Economic Excellence Chair in Neuropathology at MUSC has relocated to Texas. He has also assumed a position of professor of Neurology in the UTMB department of neurosciences.
Pappolla’s research has netted him two patents for neuroprotective compounds, and two more patents are pending. His compounds are similar to melatonin, an antioxidant that may be able to protect humans against the damaging effects of aging and diseases such as Alzheimer’s disease, cardiovascular disease and inflammation.

Pappolla believes his compounds will have commercial applications in medical treatments and nutritional supplements. His discoveries may even have potential of being use in head trauma and stroke. “I’m excited to be bak in Texas here and I’m very hopeful about the future,” Pappolla said. “It’s an exciting time for this area of research. There is a lot of demand for treatments that can slow the aging process, so the economic incentive to advance this research is there. My goal is to tap into this demand and get the products of my research into the market where they can improve people’s lives.” Pappolla’s work has tremendous commercialization potential, which means a tremendous opportunity for Texas’s citizens to benefit from additional jobs and a stronger state biotechnology cluster”, said technology associates at the McGowin Center for Neuroscience and the clinical staff at the St. Michael’s Pain and Spine Clinics.

Pappolla recently completed a sabbatical/fellowship at the University of Mississippi at Jackson, where he focused on pain management. He also served as a professor of neurology and neurosciences at Louisiana State University Health Sciences Center in New Orleans and maintained a private practice in Mississippi which was disrupted by hurricane Katrina, requiring a temporary relocation to South Carolina.

Pappolla is board certified in Pain Medicine, Neurology, Anatomic pathology, Clinical Pathology and Neuropathology. He is widely published in clinical and translational neurosciences and has extensive administrative and clinical practice experience. He has held multiple grants from the National Institutes of Health, foundations and corporations, as well as from the Department of Veterans Affairs. He has published over 80 peer-reviewed manuscripts, 12 invited reviews and book chapters and nearly 70 abstracts and his work is cited in over 600 textbooks worldwide.

Pappolla received his M.D. from the University of Buenos Aires in Argentina and his Ph.D. from the University of Catalunya in Barcelona, Spain. Following his residency training in anatomic and clinical pathology and in neurology, he completed fellowships in neuropathology at Case Western Reserve University and the Cleveland Clinic Foundation.

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